ZEISS LSM Lightfield 4D Web Demo

  • Designed for researchers pushing life science imaging forward
  • See how Lightfield 4D delivers instant volumetric imaging
  • Capture rapid biological processes without sacrificing resolution
  • Practical examples and applications to elevate your research

Built for New Discoveries

Key Features of ZEISS LSM Lightfield 4D at a glance
  • Capture Spatial Signals & Fast Dynamics

    Capture the fastest movements within whole organisms at up to 80 volumes per second – with all spatiotemporal information intact. The unique one-snap-one-volume imaging ensures that crucial events are not missed or distorted.

  • Gently Observe Organisms Over Time

    A complete Z-stack is acquired with a single illumination event, reducing light exposure and phototoxic effects to a minimum. Living samples can be imaged over long periods of time at high temporal density.

  • Speed Up Acquisition & Throughput

    The unmatched speed with which Lightfield 4D captures multi-color volumes can be used to increase the productivity of experiments. Image and analyze more samples than ever before in every session or compare multiple different sample cohorts.

  • Combine Light-Field with Confocal Imaging

    Take your experiments to the next level by pairing the flexibility of LSM (e.g., super-resolution and spectral imaging, optical sectioning of large samples, measurements of molecular dynamics) with the gentle and instant volume imaging of Lightfield 4D.

Image 4: Calcium signalling in the zebrafish brain. Courtesy of Anton Nikolaev, University of Sheffield, UK. Data acquired at Wolfson Light Microscopy Facility in the School of Biosciences at the University of Sheffield.

Capture 3D Volumes in a Single Snapshot

Experience true instant volumetric imaging. Lightfield 4D captures 3D volumes from 37 angles in a single click — no z-stack scanning needed. Researchers can record full datasets in seconds instead of minutes or hours, ideal for dynamic live samples like zebrafish or Drosophila embryos.

Ultra-Fast Imaging — up to ~80 volumes per second

Achieve ultra-fast 4D imaging at up to 80 volumes per second without sacrificing spatial resolution. Perfect for capturing neural activity, heartbeat motion, or other rapid biological phenomena in real time.

Minimise Sample Stress, Maximise Insights

Lightfield 4D uses only one illumination per capture, dramatically reducing phototoxicity and photobleaching. This makes it a super-gentle technology for long-term developmental or live-cell imaging, preserving sample health even over hours of recording.

One Microscope. Multiple Modalities.

Built as an add-on to the LSM 990 system, Lightfield 4D works seamlessly with existing ZEISS workflows (ZEN, Airyscan). Installation takes minutes, and data processing is fully automated — from raw capture to 3D rendering and quantitative analysis with ZEN or arivis software.

Register for our On-Demand web demo!

Join our experts as they demonstrate how Lightfield 4D enables instant volumetric imaging with exceptional speed and gentle illumination. Discover how this technology captures fast biological processes without compromising resolution, and how it can expand your imaging possibilities.

The session features real live-sample examples, data processing, and analysis using ZEN and arivis software. 

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